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Rainer Rupprecht Selected Research

Anxiety Disorders (Anxiety Disorder)

10/2023Neurosteroids and translocator protein 18 kDa (TSPO) in depression: implications for synaptic plasticity, cognition, and treatment options.
3/2022Neuroinflammation and psychiatric disorders: Relevance of C1q, translocator protein (18 kDa) (TSPO), and neurosteroids.
2/2014The role of allopregnanolone in depression and anxiety.
11/2012Translocator protein (18 kDa) (TSPO) as a therapeutic target for anxiety and neurologic disorders.
1/2012Recent developments in potential anxiolytic agents targeting GABAA/BzR complex or the translocator protein (18kDa) (TSPO).
1/2011Neurosteroids as neuromodulators in the treatment of anxiety disorders.
3/2008The complex roles of neurosteroids in depression and anxiety disorders.
1/2008World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the pharmacological treatment of anxiety, obsessive-compulsive and post-traumatic stress disorders - first revision.
1/2008Neuroactive steroids as endogenous modulators of anxiety.
7/2006Neuroactive steroids as modulators of depression and anxiety.
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Rainer Rupprecht Research Topics

Disease

16Anxiety Disorders (Anxiety Disorder)
10/2023 - 01/2002
16Panic Disorder (Panic Attack)
10/2014 - 01/2002
15Major Depressive Disorder (Major Depressive Disorders)
10/2023 - 06/2005
12Neuroinflammatory Diseases
01/2024 - 01/2014
12Mood Disorders (Mood Disorder)
10/2023 - 03/2002
12Tinnitus
01/2019 - 01/2012
9Sleep Deprivation
03/2016 - 05/2002
7Depressive Disorder (Melancholia)
04/2024 - 04/2004
7Neoplasms (Cancer)
10/2023 - 12/2005
7Schizophrenia (Dementia Praecox)
05/2019 - 08/2004
6Glioma (Gliomas)
02/2023 - 01/2012
5Inflammation (Inflammations)
01/2023 - 01/2014
5Mental Disorders (Mental Disorder)
03/2022 - 01/2010
4Alzheimer Disease (Alzheimer's Disease)
01/2024 - 11/2022
4Bipolar Disorder (Manic Depressive Psychosis)
05/2019 - 07/2003
3Disease Progression
01/2024 - 03/2003
3Glioblastoma (Glioblastoma Multiforme)
11/2023 - 07/2018
3Postpartum Depression (Post-Natal Depression)
10/2023 - 01/2022
3Treatment-Resistant Depressive Disorder
01/2022 - 01/2006
3Gliosis
02/2019 - 12/2010
2Mitochondrial Diseases (Mitochondrial Disease)
03/2024 - 01/2024
2Cognitive Dysfunction
10/2023 - 01/2022
2Atrophy
07/2023 - 01/2022
2Sleep Initiation and Maintenance Disorders (Insomnia)
01/2022 - 01/2019
2Infections
05/2019 - 01/2017
2Multiple Sclerosis
10/2017 - 03/2010
2Sleepiness
01/2017 - 03/2016
2Substance Withdrawal Syndrome (Withdrawal Symptoms)
01/2012 - 07/2009
2Substance-Related Disorders (Drug Abuse)
01/2010 - 01/2008
1Obesity
01/2024
1Clinical Deterioration
01/2024
1COVID-19
11/2023
1Wounds and Injuries (Trauma)
10/2023
1Dementia (Dementias)
10/2023
1Progressive Multifocal Leukoencephalopathy
06/2022
1Acute Pain
05/2022
1Tauopathies
01/2021
1Necrosis
01/2021
1Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)
01/2021
1Corticobasal Degeneration
01/2021

Drug/Important Bio-Agent (IBA)

22Proteins (Proteins, Gene)FDA Link
04/2024 - 07/2003
20NeurosteroidsIBA
10/2023 - 01/2002
19Antidepressive Agents (Antidepressants)IBA
03/2024 - 03/2003
12LigandsIBA
04/2024 - 07/2009
8Biomarkers (Surrogate Marker)IBA
01/2024 - 12/2010
7Anti-Anxiety Agents (Anxiolytics)IBA
01/2012 - 01/2003
7TetragastrinIBA
01/2011 - 02/2003
6GABA-A Receptors (GABA(A) Receptor)IBA
11/2012 - 01/2002
6gamma-Aminobutyric Acid (GABA)IBA
07/2009 - 01/2002
5Amyloid (Amyloid Fibrils)IBA
01/2024 - 11/2022
5BenzodiazepinesIBA
10/2023 - 05/2005
5Amino AcidsFDA Link
02/2023 - 07/2003
5Antipsychotic Agents (Antipsychotics)IBA
06/2014 - 11/2005
4Pregnanolone (Allopregnanolone)IBA
10/2023 - 02/2014
3etifoxineIBA
04/2024 - 01/2023
3Serotonin (5 Hydroxytryptamine)IBA
03/2024 - 11/2005
3N- benzyl- N- ethyl- 2- (7,8- dihydro- 7- methyl- 8- oxo- 2- phenyl- 9H- purin- 9- yl)acetamideIBA
10/2023 - 07/2009
3zuranoloneIBA
10/2023 - 01/2022
3brexanoloneIBA
10/2023 - 01/2022
3CytokinesIBA
01/2021 - 05/2019
3Quetiapine Fumarate (Seroquel)FDA Link
06/2014 - 01/2012
3Mirtazapine (Rexer)FDA LinkGeneric
01/2009 - 03/2003
3Sodium LactateFDA LinkGeneric
01/2006 - 02/2003
2Interleukin-6 (Interleukin 6)IBA
01/2020 - 05/2019
2ChemokinesIBA
05/2019 - 01/2017
2Retinaldehyde (Retinal)IBA
02/2019 - 01/2014
2Hypnotics and Sedatives (Sedatives)IBA
01/2019 - 01/2012
2Butyric Acid (Butanoic Acid)IBA
11/2009 - 04/2004
2GTP-Binding Proteins (G-Protein)IBA
07/2002 - 03/2002
1Psychotropic Drugs (Psychoactive Drugs)IBA
11/2023
1Peptides (Polypeptides)IBA
10/2023
1MethyltransferasesIBA
10/2023
1DNA (Deoxyribonucleic Acid)IBA
10/2023
1Temozolomide (Temodar)FDA LinkGeneric
10/2023
1Telomerase (Telomerase Reverse Transcriptase)IBA
10/2023
1Complement System Proteins (Complement)IBA
10/2023
1Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
10/2023
1Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
06/2022
1Glucose (Dextrose)FDA LinkGeneric
06/2022
1Opioid Analgesics (Opioids)IBA
05/2022
1Immunologic Factors (Immunomodulators)IBA
03/2022
1Diazepam (Valium)FDA LinkGeneric
01/2022
1Minocycline (Cyclops)FDA LinkGeneric
01/2022
1Serotonin AgentsIBA
01/2022
1Interleukin-17 (Interleukin 17)IBA
01/2021
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2021
1Interleukin-16 (Interleukin 16)IBA
01/2021
1InterleukinsIBA
01/2021
1Interleukin-15 (Interleukin 15)IBA
01/2021
1Interleukin-12 (IL 12)IBA
01/2021
1Interleukin-7 (Interleukin 7)IBA
01/2021
1CC ChemokinesIBA
01/2020
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2019
1Interleukin-1beta (Interleukin 1 beta)IBA
05/2019

Therapy/Procedure

14Transcranial Magnetic Stimulation
01/2018 - 05/2002
7Therapeutics
05/2021 - 01/2007
5Drug Therapy (Chemotherapy)
01/2017 - 01/2006
2Transcranial Direct Current Stimulation
01/2019 - 12/2017
2Combined Modality Therapy
07/2018 - 01/2018
1Radiotherapy
10/2023